{
  "company": {
    "name": "PAQ Therapeutics",
    "website": "https://paqtx.com/",
    "record": "https://startuphistory.org/c/paqtx.com"
  },
  "status": null,
  "history_since": "2021-10-20T15:25:33.000Z",
  "baseline": {
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    "observed_at": "2021-10-20T15:25:33.000Z",
    "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
    "description": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
    "evidence": "https://web.archive.org/web/20211020152533/https://www.paqtx.com/",
    "evidence_kind": "internet_archive",
    "facts": null,
    "basis": "first_observation",
    "is_change": false
  },
  "live_captures": 1,
  "last_checked": "2026-11-06T19:57:24.408Z",
  "live_status": null,
  "messaging": [
    {
      "quote_observed_at": "2025-01-16T10:37:35.000Z",
      "variants": [
        {
          "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
          "subhead": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
          "observed_at": "2021-10-20T15:25:33.000Z",
          "evidence": "https://web.archive.org/web/20211020152533/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
          "subhead": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
          "observed_at": "2022-05-24T11:05:07.000Z",
          "evidence": "https://web.archive.org/web/20220524110507/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
          "subhead": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
          "observed_at": "2022-09-25T00:47:52.000Z",
          "evidence": "https://web.archive.org/web/20220925004752/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
          "subhead": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
          "observed_at": "2023-02-09T08:15:02.000Z",
          "evidence": "https://web.archive.org/web/20230209081502/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
          "subhead": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
          "observed_at": "2023-07-24T17:12:06.000Z",
          "evidence": "https://web.archive.org/web/20230724171206/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
          "subhead": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
          "observed_at": "2024-09-10T16:22:31.000Z",
          "evidence": "https://web.archive.org/web/20240910162231/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
          "subhead": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
          "observed_at": "2025-01-16T10:37:35.000Z",
          "evidence": "https://web.archive.org/web/20250116103735/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "Harnessing the Power of Autophagy to Restore Health and Cure Disease",
      "subhead": "Our team is united by a visionary goal – to pioneer a new approach to restore health and cure disease through the power of autophagy.",
      "from": "2021-10-20T15:25:33.000Z",
      "to": "2025-01-16T10:37:35.000Z",
      "captures": 7,
      "evidence": "https://web.archive.org/web/20250116103735/https://www.paqtx.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "between": {
          "from": "2021-10-20T15:25:33.000Z",
          "to": "2025-01-16T10:37:35.000Z"
        }
      },
      "current": false
    },
    {
      "quote_observed_at": "2026-11-06T19:57:24.408Z",
      "variants": [
        {
          "headline": "Beyond Inhibition – Unlocking the Power of KRAS Degradation",
          "subhead": "PAQ Therapeutics is developing KRAS degraders for deadly cancers without good treatment options.",
          "observed_at": "2025-07-21T15:19:01.000Z",
          "evidence": "https://web.archive.org/web/20250721151901/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Beyond Inhibition – Unlocking the Power of KRAS Degradation",
          "subhead": "PAQ Therapeutics is developing KRAS degraders for deadly cancers without good treatment options.",
          "observed_at": "2026-03-12T00:35:58.000Z",
          "evidence": "https://web.archive.org/web/20260312003558/https://www.paqtx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Beyond Inhibition – Unlocking the Power of KRAS Degradation",
          "subhead": "PAQ Therapeutics is developing KRAS degraders for deadly cancers without good treatment options.",
          "observed_at": "2026-11-06T19:57:24.408Z",
          "evidence": "https://www.paqtx.com/",
          "evidence_kind": "live_capture"
        }
      ],
      "headline": "Beyond Inhibition – Unlocking the Power of KRAS Degradation",
      "subhead": "PAQ Therapeutics is developing KRAS degraders for deadly cancers without good treatment options.",
      "from": "2025-07-21T15:19:01.000Z",
      "to": "2026-11-06T19:57:24.408Z",
      "captures": 3,
      "evidence": "https://www.paqtx.com/",
      "evidence_kind": "live_capture",
      "seen": {
        "between": {
          "from": "2025-07-21T15:19:01.000Z",
          "to": "2026-11-06T19:57:24.408Z"
        }
      },
      "current": true
    }
  ],
  "changes": [
    {
      "n": 1,
      "id": "page-370ab78901ff4c59e266d15e6d265e22fc795d8dd6ecf1f1739b8048d69bd510:e302eec7b3ab09aaedc33ec042446024dac03584fdda83953af03615069dd2d6:hiring:20dd4c09cc4ab0aa",
      "before_evidence": "https://web.archive.org/web/20211020152533/https://www.paqtx.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "hiring",
      "label": "Hiring",
      "summary": "Added a careers page.",
      "between": {
        "from": "2021-10-20T15:25:33.000Z",
        "to": "2022-05-24T11:05:07.000Z"
      },
      "evidence": "https://web.archive.org/web/20220524110507/https://www.paqtx.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/added-careers-page"
    },
    {
      "n": 2,
      "id": "page-3319e932efa76cd9f2685946ae80676ad4e417d99565b912763486a9919225f6:a223122b368af6fde3e24ca0003f7237d944c355d7f8adba521ecb0adfb662f6:headline:78ffe218f8d2de7e",
      "before_evidence": "https://web.archive.org/web/20250116103735/https://www.paqtx.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “Harnessing the Power of Autophagy to Restore Health and Cure Disease” to “Beyond Inhibition – Unlocking the Power of KRAS Degradation”.",
      "between": {
        "from": "2025-01-16T10:37:35.000Z",
        "to": "2025-07-21T15:19:01.000Z"
      },
      "evidence": "https://web.archive.org/web/20250721151901/https://www.paqtx.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
    }
  ],
  "update": {
    "headline": "PAQ Therapeutics updates homepage headline toward KRAS degradation",
    "summary": "PAQ Therapeutics now emphasizes “KRAS Degradation” in its homepage headline, replacing a broader autophagy-focused message. The company previously added a careers page.",
    "points": [
      {
        "text": "Between January 2025 and July 2025, PAQ Therapeutics changed its homepage headline from “Harnessing the Power of Autophagy to Restore Health and Cure Disease” to “Beyond Inhibition – Unlocking the Power of KRAS Degradation”.",
        "kind": "fact",
        "changes": [
          2
        ]
      },
      {
        "text": "The updated homepage headline between January 2025 and July 2025 suggests a narrower emphasis on KRAS degradation compared with the earlier broader autophagy framing.",
        "kind": "interpretation",
        "changes": [
          2
        ]
      },
      {
        "text": "Between October 2021 and May 2022, PAQ Therapeutics added a careers page.",
        "kind": "fact",
        "changes": [
          1
        ]
      }
    ],
    "written_at": "2026-11-07T20:34:44.543Z",
    "basis": "ai_analysis",
    "model": "gpt-5.1-2025-11-13"
  },
  "method": {
    "version": "messaging-v1",
    "description": "https://startuphistory.org/method"
  },
  "license": "CC-BY-4.0",
  "cite": "StartupHistory, “PAQ Therapeutics” company record, https://startuphistory.org/c/paqtx.com"
}