{
  "company": {
    "name": "Orbis Medicines",
    "website": "https://orbismedicines.com/",
    "record": "https://startuphistory.org/c/orbismedicines.com"
  },
  "status": null,
  "history_since": "2023-11-07T15:11:49.000Z",
  "baseline": {
    "snapshot_id": "acbb34aaa68d2fc5830df25d559406adc457f2f12f05594974c8c346fe641f19",
    "observed_at": "2023-11-07T15:11:49.000Z",
    "headline": "Reshaping the future of drug discovery.",
    "description": null,
    "evidence": "https://web.archive.org/web/20231107151149/https://www.orbismedicines.com/",
    "evidence_kind": "internet_archive",
    "facts": null,
    "basis": "first_observation",
    "is_change": false
  },
  "live_captures": 1,
  "last_checked": "2026-11-06T19:51:16.977Z",
  "live_status": null,
  "messaging": [
    {
      "quote_observed_at": "2026-02-25T22:33:19.000Z",
      "variants": [
        {
          "headline": "Reshaping the future of drug discovery.",
          "subhead": null,
          "observed_at": "2023-11-07T15:11:49.000Z",
          "evidence": "https://web.archive.org/web/20231107151149/https://www.orbismedicines.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "A new era for oral macrocycle drug discovery",
          "subhead": null,
          "observed_at": "2024-02-29T18:24:47.000Z",
          "evidence": "https://web.archive.org/web/20240229182447/https://www.orbismedicines.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "A new era for oral macrocycle drug discovery",
          "subhead": null,
          "observed_at": "2024-07-15T14:19:01.000Z",
          "evidence": "https://web.archive.org/web/20240715141901/https://www.orbismedicines.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "A new era for oral macrocycle drug discovery",
          "subhead": null,
          "observed_at": "2025-01-01T12:24:14.000Z",
          "evidence": "https://web.archive.org/web/20250101122414/https://www.orbismedicines.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "A new era for oral macrocycle drug discovery",
          "subhead": null,
          "observed_at": "2026-02-25T22:33:19.000Z",
          "evidence": "https://web.archive.org/web/20260225223319/https://www.orbismedicines.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "A new era for oral macrocycle drug discovery",
      "subhead": null,
      "from": "2023-11-07T15:11:49.000Z",
      "to": "2026-02-25T22:33:19.000Z",
      "captures": 5,
      "evidence": "https://web.archive.org/web/20260225223319/https://www.orbismedicines.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "between": {
          "from": "2023-11-07T15:11:49.000Z",
          "to": "2026-02-25T22:33:19.000Z"
        }
      },
      "current": false
    },
    {
      "quote_observed_at": "2026-11-06T19:51:16.977Z",
      "variants": [
        {
          "headline": "Oral biologics, solved with intelligent chemistry",
          "subhead": null,
          "observed_at": "2026-09-19T03:12:18.000Z",
          "evidence": "https://web.archive.org/web/20260919031218/https://www.orbismedicines.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Oral biologics, solved with intelligent chemistry",
          "subhead": null,
          "observed_at": "2026-11-06T19:51:16.977Z",
          "evidence": "https://www.orbismedicines.com/",
          "evidence_kind": "live_capture"
        }
      ],
      "headline": "Oral biologics, solved with intelligent chemistry",
      "subhead": null,
      "from": "2026-09-19T03:12:18.000Z",
      "to": "2026-11-06T19:51:16.977Z",
      "captures": 2,
      "evidence": "https://www.orbismedicines.com/",
      "evidence_kind": "live_capture",
      "seen": {
        "between": {
          "from": "2026-09-19T03:12:18.000Z",
          "to": "2026-11-06T19:51:16.977Z"
        }
      },
      "current": true
    }
  ],
  "changes": [
    {
      "n": 1,
      "id": "classifier-acbb34aaa68d2fc5830df25d559406adc457f2f12f05594974c8c346fe641f19:72b94d272aba2fca69c60d7313a1eabda1a82b918cb6c86972f778d6e4c3d7e8:repositioning",
      "before_evidence": "https://web.archive.org/web/20231107151149/https://www.orbismedicines.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "repositioning",
      "label": "Messaging",
      "summary": "Changed its homepage headline from “Reshaping the future of drug discovery.” to “A new era for oral macrocycle drug discovery”.",
      "between": {
        "from": "2023-11-07T15:11:49.000Z",
        "to": "2024-02-29T18:24:47.000Z"
      },
      "evidence": "https://web.archive.org/web/20240229182447/https://www.orbismedicines.com/",
      "evidence_kind": "internet_archive",
      "basis": "classifier",
      "topic": "https://startuphistory.org/t/repositioned"
    },
    {
      "n": 2,
      "id": "classifier-1e5fa3bae62daf3b8006b4f8a0d8862ae369136e6bba17cadb260bbc02476209:5010fc7d061f4eab2e63d181489f75e245d87f10a25af41b5fea0a3edf8bb911:repositioning",
      "before_evidence": "https://web.archive.org/web/20260225223319/https://www.orbismedicines.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "repositioning",
      "label": "Messaging",
      "summary": "Changed its homepage headline from “A new era for oral macrocycle drug discovery” to “Oral biologics, solved with intelligent chemistry”.",
      "between": {
        "from": "2026-02-25T22:33:19.000Z",
        "to": "2026-09-19T03:12:18.000Z"
      },
      "evidence": "https://web.archive.org/web/20260919031218/https://www.orbismedicines.com/",
      "evidence_kind": "internet_archive",
      "basis": "classifier",
      "topic": "https://startuphistory.org/t/repositioned"
    },
    {
      "n": 3,
      "id": "page-1e5fa3bae62daf3b8006b4f8a0d8862ae369136e6bba17cadb260bbc02476209:5010fc7d061f4eab2e63d181489f75e245d87f10a25af41b5fea0a3edf8bb911:hiring:20dd4c09cc4ab0aa",
      "before_evidence": "https://web.archive.org/web/20260225223319/https://www.orbismedicines.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "hiring",
      "label": "Hiring",
      "summary": "Added a careers page.",
      "between": {
        "from": "2026-02-25T22:33:19.000Z",
        "to": "2026-09-19T03:12:18.000Z"
      },
      "evidence": "https://web.archive.org/web/20260919031218/https://www.orbismedicines.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/added-careers-page"
    }
  ],
  "update": {
    "headline": "Orbis Medicines updates focus and adds a careers page",
    "summary": "Orbis Medicines has updated its homepage messaging about its drug discovery focus and added a careers page. The changes suggest an emphasis on oral biologics and possible organizational development.",
    "points": [
      {
        "text": "Between November 2023 and February 2024, Orbis Medicines changed its homepage headline from “Reshaping the future of drug discovery.” to “A new era for oral macrocycle drug discovery”.",
        "kind": "fact",
        "changes": [
          1
        ]
      },
      {
        "text": "Between February 2026 and September 2026, Orbis Medicines changed its homepage headline from “A new era for oral macrocycle drug discovery” to “Oral biologics, solved with intelligent chemistry”.",
        "kind": "fact",
        "changes": [
          2
        ]
      },
      {
        "text": "A classifier read the homepage headline changes between November 2023 and September 2026 as repositionings in how Orbis Medicines presents its drug discovery focus.",
        "kind": "interpretation",
        "changes": [
          1,
          2
        ]
      },
      {
        "text": "Between February 2026 and September 2026, Orbis Medicines added a careers page, which may point to organizational development or future team changes.",
        "kind": "interpretation",
        "changes": [
          3
        ]
      }
    ],
    "written_at": "2026-11-07T20:39:07.076Z",
    "basis": "ai_analysis",
    "model": "gpt-5.1-2025-11-13"
  },
  "method": {
    "version": "messaging-v1",
    "description": "https://startuphistory.org/method"
  },
  "license": "CC-BY-4.0",
  "cite": "StartupHistory, “Orbis Medicines” company record, https://startuphistory.org/c/orbismedicines.com"
}