{
  "company": {
    "name": "OpenProtein.AI",
    "website": "https://openprotein.ai/",
    "record": "https://startuphistory.org/c/openprotein.ai"
  },
  "status": null,
  "history_since": "2023-05-30T20:33:38.000Z",
  "baseline": {
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    "observed_at": "2023-05-30T20:33:38.000Z",
    "headline": "The OpenProtein.AI web platform offers machine learning-powered protein engineering at your fingertips.",
    "description": "Our deep learning platform accelerates protein engineering.",
    "evidence": "https://web.archive.org/web/20230530203338/https://www.openprotein.ai/",
    "evidence_kind": "internet_archive",
    "facts": null,
    "basis": "first_observation",
    "is_change": false
  },
  "live_captures": 1,
  "last_checked": "2026-11-06T19:47:28.046Z",
  "live_status": null,
  "messaging": [
    {
      "quote_observed_at": "2023-09-27T19:33:33.000Z",
      "variants": [
        {
          "headline": "The OpenProtein.AI web platform offers machine learning-powered protein engineering at your fingertips.",
          "subhead": "Our deep learning platform accelerates protein engineering.",
          "observed_at": "2023-05-30T20:33:38.000Z",
          "evidence": "https://web.archive.org/web/20230530203338/https://www.openprotein.ai/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "The OpenProtein.AI web platform offers machine learning-powered protein engineering at your fingertips.",
          "subhead": "Our deep learning platform accelerates protein engineering.",
          "observed_at": "2023-09-27T19:33:33.000Z",
          "evidence": "https://web.archive.org/web/20230927193333/https://www.openprotein.ai/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "The OpenProtein.AI web platform offers machine learning-powered protein engineering at your fingertips.",
      "subhead": "Our deep learning platform accelerates protein engineering.",
      "from": "2023-05-30T20:33:38.000Z",
      "to": "2023-09-27T19:33:33.000Z",
      "captures": 2,
      "evidence": "https://web.archive.org/web/20230927193333/https://www.openprotein.ai/",
      "evidence_kind": "internet_archive",
      "seen": {
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          "to": "2023-09-27T19:33:33.000Z"
        }
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      "current": false
    },
    {
      "quote_observed_at": "2026-03-21T13:01:28.000Z",
      "variants": [
        {
          "headline": "Big data or small data",
          "subhead": "Our deep learning platform accelerates protein engineering.",
          "observed_at": "2024-03-03T00:25:53.000Z",
          "evidence": "https://web.archive.org/web/20240303002553/https://www.openprotein.ai/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Big data or small data",
          "subhead": "Our deep learning platform accelerates protein engineering. Design better proteins using in-house machine learning/generative AI models, with small datasets.",
          "observed_at": "2024-07-14T01:15:16.000Z",
          "evidence": "https://web.archive.org/web/20240714011516/https://www.openprotein.ai/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Big data or small data",
          "subhead": "Our deep learning platform accelerates protein engineering. Design better proteins using in-house machine learning/generative AI models, with small datasets.",
          "observed_at": "2025-02-16T16:05:51.000Z",
          "evidence": "https://web.archive.org/web/20250216160551/https://www.openprotein.ai/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Big data or small data",
          "subhead": "Our deep learning platform accelerates protein engineering. Design better proteins using in-house machine learning/generative AI models, with small datasets.",
          "observed_at": "2025-08-05T16:49:15.000Z",
          "evidence": "https://web.archive.org/web/20250805164915/https://www.openprotein.ai/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Big data or small data",
          "subhead": "OpenProtein develops state-of-the-art protein language models and a protein design cloud platform that enables users to design, evaluate, and optimize proteins with high precision and efficiency. Expl",
          "observed_at": "2026-03-21T13:01:28.000Z",
          "evidence": "https://web.archive.org/web/20260321130128/https://www.openprotein.ai/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "Big data or small data",
      "subhead": "OpenProtein develops state-of-the-art protein language models and a protein design cloud platform that enables users to design, evaluate, and optimize proteins with high precision and efficiency. Expl",
      "from": "2024-03-03T00:25:53.000Z",
      "to": "2026-03-21T13:01:28.000Z",
      "captures": 5,
      "evidence": "https://web.archive.org/web/20260321130128/https://www.openprotein.ai/",
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    },
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      "quote_observed_at": "2026-11-06T19:47:28.046Z",
      "variants": [
        {
          "headline": "OpenProtein.AI — The AI Cloud for Protein Design",
          "subhead": "OpenProtein develops state-of-the-art protein language models and a protein design cloud platform that enables users to design, evaluate, and optimize proteins with high precision and efficiency. Expl",
          "observed_at": "2026-10-15T22:45:16.000Z",
          "evidence": "https://web.archive.org/web/20261015224516/https://openprotein.ai/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "OpenProtein.AI — The AI Cloud for Protein Design",
          "subhead": "OpenProtein develops state-of-the-art protein language models and a protein design cloud platform that enables users to design, evaluate, and optimize proteins with high precision and efficiency. Expl",
          "observed_at": "2026-11-06T19:47:28.046Z",
          "evidence": "https://openprotein.ai/",
          "evidence_kind": "live_capture"
        }
      ],
      "headline": "OpenProtein.AI — The AI Cloud for Protein Design",
      "subhead": "OpenProtein develops state-of-the-art protein language models and a protein design cloud platform that enables users to design, evaluate, and optimize proteins with high precision and efficiency. Expl",
      "from": "2026-10-15T22:45:16.000Z",
      "to": "2026-11-06T19:47:28.046Z",
      "captures": 2,
      "evidence": "https://openprotein.ai/",
      "evidence_kind": "live_capture",
      "seen": {
        "between": {
          "from": "2026-10-15T22:45:16.000Z",
          "to": "2026-11-06T19:47:28.046Z"
        }
      },
      "current": true
    }
  ],
  "changes": [
    {
      "n": 1,
      "id": "page-ef3cf1f181af212360d60904b5e16a1ffcabbd28669c13c306df6670c79a328f:37503a356f69fcb6944247e184aea84b0454386751472f885b602e2a3449408a:headline:7a99cecce1f9f935",
      "before_evidence": "https://web.archive.org/web/20230927193333/https://www.openprotein.ai/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “The OpenProtein.AI web platform offers machine learning-powered protein engineering at your fingertips.” to “Big data or small data”.",
      "between": {
        "from": "2023-09-27T19:33:33.000Z",
        "to": "2024-03-03T00:25:53.000Z"
      },
      "evidence": "https://web.archive.org/web/20240303002553/https://www.openprotein.ai/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
    },
    {
      "n": 2,
      "id": "page-0298bac9972a1b6d59d3a1053fb9a9df4a280a55f3c082a00e16da69821ad708:5a4e4b373917760f99d4581e402bb63eb96c9199bf20d2d7d8b2ff4a9f3ebcc0:headline:c452f12fa49009cf",
      "before_evidence": "https://web.archive.org/web/20260321130128/https://www.openprotein.ai/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “Big data or small data” to “OpenProtein.AI — The AI Cloud for Protein Design”.",
      "between": {
        "from": "2026-03-21T13:01:28.000Z",
        "to": "2026-10-15T22:45:16.000Z"
      },
      "evidence": "https://web.archive.org/web/20261015224516/https://openprotein.ai/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
    },
    {
      "n": 3,
      "id": "page-0298bac9972a1b6d59d3a1053fb9a9df4a280a55f3c082a00e16da69821ad708:5a4e4b373917760f99d4581e402bb63eb96c9199bf20d2d7d8b2ff4a9f3ebcc0:gtm:71fb5032b8ee999a",
      "before_evidence": "https://web.archive.org/web/20260321130128/https://www.openprotein.ai/",
      "before_evidence_kind": "internet_archive",
      "kind": "gtm",
      "label": "Go-to-market",
      "summary": "Closed its waitlist and opened sign-up.",
      "between": {
        "from": "2026-03-21T13:01:28.000Z",
        "to": "2026-10-15T22:45:16.000Z"
      },
      "evidence": "https://web.archive.org/web/20261015224516/https://openprotein.ai/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/opened-sign-up"
    }
  ],
  "update": {
    "headline": "OpenProtein.AI updates positioning and opens sign-up",
    "summary": "OpenProtein.AI has updated its homepage messaging and moved from a waitlist to open sign-up. The company’s current headline emphasizes an AI cloud for protein design.",
    "points": [
      {
        "text": "Between September 2023 and March 2024, OpenProtein.AI changed its homepage headline from text about a web platform offering machine learning-powered protein engineering to “Big data or small data”.",
        "kind": "fact",
        "changes": [
          1
        ]
      },
      {
        "text": "Between March 2026 and October 2026, OpenProtein.AI changed its homepage headline to “OpenProtein.AI — The AI Cloud for Protein Design”.",
        "kind": "fact",
        "changes": [
          2
        ]
      },
      {
        "text": "Between March 2026 and October 2026, OpenProtein.AI closed its waitlist and opened sign-up.",
        "kind": "fact",
        "changes": [
          3
        ]
      },
      {
        "text": "The move to describe itself as an “AI Cloud for Protein Design” and to open sign-up between March 2026 and October 2026 suggests a focus on broader product access under this positioning.",
        "kind": "interpretation",
        "changes": [
          2,
          3
        ]
      }
    ],
    "written_at": "2026-11-07T14:35:17.630Z",
    "basis": "ai_analysis",
    "model": "gpt-5.1-2025-11-13"
  },
  "method": {
    "version": "messaging-v1",
    "description": "https://startuphistory.org/method"
  },
  "license": "CC-BY-4.0",
  "cite": "StartupHistory, “OpenProtein.AI” company record, https://startuphistory.org/c/openprotein.ai"
}