{
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      "variants": [
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          "headline": "Advancing a new approach to schizophrenia: TARGETING NEGATIVE SYMPTOMS",
          "subhead": "Minerva Neurosciences is advancing roluperidone, a potential first-in-class treatment designed to address the negative symptoms of schizophrenia.",
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          "evidence": "https://minervaneurosciences.com/",
          "evidence_kind": "live_capture"
        }
      ],
      "headline": "Advancing a new approach to schizophrenia: TARGETING NEGATIVE SYMPTOMS",
      "subhead": "Minerva Neurosciences is advancing roluperidone, a potential first-in-class treatment designed to address the negative symptoms of schizophrenia.",
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      "to": "2026-11-06T17:41:31.438Z",
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      "evidence_kind": "live_capture",
      "seen": {
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      "id": "page-841045ef0727ec601c4be714d35cac00d3f50a848cfc4cbc2bb0b89c293be171:2dfc0f1ca3d9e4c667f5eb1328d2f556e02050a7bd1ab0cf9d0fab25b7ed110b:headline:2ec8354c86b7be2e",
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      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “Minerva Neurosciences, Inc.” to “Clinical Expertise and Patient Focus”.",
      "between": {
        "from": "2015-07-03T02:58:11.000Z",
        "to": "2017-03-19T01:34:50.000Z"
      },
      "evidence": "https://web.archive.org/web/20170319013450/http://www.minervaneurosciences.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
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    {
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      "id": "classifier-1c31b7a4cf4725a82bceadab7ee64fc516ca4a7ca8fee4d10745c747c63ce418:4b63e73914816231d115802f55732adfa3323723b2c1ea05db95af0a99a1f8ad:repositioning",
      "before_evidence": "https://web.archive.org/web/20260716015712/https://www.minervaneurosciences.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "repositioning",
      "label": "Messaging",
      "summary": "Changed its homepage headline from “Clinical Expertise and Patient Focus” to “Advancing a new approach to schizophrenia: TARGETING NEGATIVE SYMPTOMS”.",
      "between": {
        "from": "2026-07-16T01:57:12.000Z",
        "to": "2026-11-06T17:41:31.438Z"
      },
      "evidence": "https://minervaneurosciences.com/",
      "evidence_kind": "live_capture",
      "basis": "classifier",
      "topic": "https://startuphistory.org/t/repositioned"
    }
  ],
  "update": {
    "headline": "Minerva Neurosciences highlights schizophrenia negative symptoms",
    "summary": "Minerva Neurosciences has updated its homepage messaging to emphasize a new approach to schizophrenia focused on negative symptoms, shifting away from its earlier broad “clinical expertise and patient focus” positioning.",
    "points": [
      {
        "text": "Between July 2015 and March 2017, Minerva Neurosciences changed its homepage headline from “Minerva Neurosciences, Inc.” to “Clinical Expertise and Patient Focus”.",
        "kind": "fact",
        "changes": [
          1
        ]
      },
      {
        "text": "Between July 2026 and November 2026, Minerva Neurosciences changed its homepage headline from “Clinical Expertise and Patient Focus” to “Advancing a new approach to schizophrenia: TARGETING NEGATIVE SYMPTOMS”.",
        "kind": "fact",
        "changes": [
          2
        ]
      },
      {
        "text": "A classifier read the latest homepage change between July 2026 and November 2026 as a repositioning toward schizophrenia and negative symptoms, which suggests a narrower focus compared with the earlier broader clinical positioning.",
        "kind": "interpretation",
        "changes": [
          2,
          1
        ]
      }
    ],
    "written_at": "2026-11-07T16:01:48.258Z",
    "basis": "ai_analysis",
    "model": "gpt-5.1-2025-11-13"
  },
  "method": {
    "version": "messaging-v1",
    "description": "https://startuphistory.org/method"
  },
  "license": "CC-BY-4.0",
  "cite": "StartupHistory, “Minerva Neurosciences” company record, https://startuphistory.org/c/minervaneurosciences.com"
}