{
  "company": {
    "name": "Junevity",
    "website": "https://junevity.com/",
    "record": "https://startuphistory.org/c/junevity.com"
  },
  "status": null,
  "history_since": "2024-05-28T08:26:34.000Z",
  "baseline": {
    "snapshot_id": "7f195ae4e0b431d9e5781e589d7ad02f37524059f5bde22b581b046dd0a07848",
    "observed_at": "2024-05-28T08:26:34.000Z",
    "headline": "TRANSCRIPTION FACTORS",
    "description": "Junevity's mission is to rewind diseases of aging by targeting transcription factors with novel medicines.",
    "evidence": "https://web.archive.org/web/20240528082634/https://www.junevity.com/",
    "evidence_kind": "internet_archive",
    "facts": null,
    "basis": "first_observation",
    "is_change": false
  },
  "live_captures": 1,
  "last_checked": "2026-11-06T17:28:16.780Z",
  "live_status": null,
  "messaging": [
    {
      "quote_observed_at": "2024-05-28T08:26:34.000Z",
      "variants": [
        {
          "headline": "TRANSCRIPTION FACTORS",
          "subhead": "Junevity's mission is to rewind diseases of aging by targeting transcription factors with novel medicines.",
          "observed_at": "2024-05-28T08:26:34.000Z",
          "evidence": "https://web.archive.org/web/20240528082634/https://www.junevity.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "TRANSCRIPTION FACTORS",
      "subhead": "Junevity's mission is to rewind diseases of aging by targeting transcription factors with novel medicines.",
      "from": "2024-05-28T08:26:34.000Z",
      "to": "2024-05-28T08:26:34.000Z",
      "captures": 1,
      "evidence": "https://web.archive.org/web/20240528082634/https://www.junevity.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "on": "2024-05-28T08:26:34.000Z"
      },
      "current": false
    },
    {
      "quote_observed_at": "2025-01-12T06:32:47.000Z",
      "variants": [
        {
          "headline": "CELL RESET FOR LONGEVITY",
          "subhead": "Junevity develops novel therapeutics to rewind metabolic disease.",
          "observed_at": "2025-01-12T06:32:47.000Z",
          "evidence": "https://web.archive.org/web/20250112063247/https://www.junevity.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "CELL RESET FOR LONGEVITY",
      "subhead": "Junevity develops novel therapeutics to rewind metabolic disease.",
      "from": "2025-01-12T06:32:47.000Z",
      "to": "2025-01-12T06:32:47.000Z",
      "captures": 1,
      "evidence": "https://web.archive.org/web/20250112063247/https://www.junevity.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "on": "2025-01-12T06:32:47.000Z"
      },
      "current": false
    },
    {
      "quote_observed_at": "2025-12-03T23:44:18.000Z",
      "variants": [
        {
          "headline": "Cell Reprogramming with siRNA",
          "subhead": "Junevity is pioneering cell reprogramming with siRNA to extend human healthspan and lifespan.",
          "observed_at": "2025-12-03T23:44:18.000Z",
          "evidence": "https://web.archive.org/web/20251203234418/https://www.junevity.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "Cell Reprogramming with siRNA",
      "subhead": "Junevity is pioneering cell reprogramming with siRNA to extend human healthspan and lifespan.",
      "from": "2025-12-03T23:44:18.000Z",
      "to": "2025-12-03T23:44:18.000Z",
      "captures": 1,
      "evidence": "https://web.archive.org/web/20251203234418/https://www.junevity.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "on": "2025-12-03T23:44:18.000Z"
      },
      "current": false
    },
    {
      "quote_observed_at": "2026-11-06T17:28:16.780Z",
      "variants": [
        {
          "headline": "Reset gene networks to reverse disease, starting with siRNA for obesity",
          "subhead": "Junevity is a biotechnology company resetting gene networks with siRNA therapeutics to reverse disease.",
          "observed_at": "2026-11-06T17:28:16.780Z",
          "evidence": "https://www.junevity.com/",
          "evidence_kind": "live_capture"
        }
      ],
      "headline": "Reset gene networks to reverse disease, starting with siRNA for obesity",
      "subhead": "Junevity is a biotechnology company resetting gene networks with siRNA therapeutics to reverse disease.",
      "from": "2026-11-06T17:28:16.780Z",
      "to": "2026-11-06T17:28:16.780Z",
      "captures": 1,
      "evidence": "https://www.junevity.com/",
      "evidence_kind": "live_capture",
      "seen": {
        "on": "2026-11-06T17:28:16.780Z"
      },
      "current": true
    }
  ],
  "changes": [
    {
      "n": 1,
      "id": "classifier-7f195ae4e0b431d9e5781e589d7ad02f37524059f5bde22b581b046dd0a07848:396a1c562e91b1a63280e1d49f369ca159ca59798b9c5879ec57d1c21c3b0ebc:repositioning",
      "before_evidence": "https://web.archive.org/web/20240528082634/https://www.junevity.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "repositioning",
      "label": "Messaging",
      "summary": "Changed its homepage headline from “TRANSCRIPTION FACTORS” to “CELL RESET FOR LONGEVITY”.",
      "between": {
        "from": "2024-05-28T08:26:34.000Z",
        "to": "2025-01-12T06:32:47.000Z"
      },
      "evidence": "https://web.archive.org/web/20250112063247/https://www.junevity.com/",
      "evidence_kind": "internet_archive",
      "basis": "classifier",
      "topic": "https://startuphistory.org/t/repositioned"
    },
    {
      "n": 2,
      "id": "page-396a1c562e91b1a63280e1d49f369ca159ca59798b9c5879ec57d1c21c3b0ebc:7e21c70e110e3773627e447ddc00d074e374f9791f970b87f5d0320426bb8617:headline:9b30e0b9650bc1e8",
      "before_evidence": "https://web.archive.org/web/20250112063247/https://www.junevity.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “CELL RESET FOR LONGEVITY” to “Cell Reprogramming with siRNA”.",
      "between": {
        "from": "2025-01-12T06:32:47.000Z",
        "to": "2025-12-03T23:44:18.000Z"
      },
      "evidence": "https://web.archive.org/web/20251203234418/https://www.junevity.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
    },
    {
      "n": 3,
      "id": "page-7e21c70e110e3773627e447ddc00d074e374f9791f970b87f5d0320426bb8617:e6dfdce646da4bf0a86a975057085b6038de61a72c14b43788c4fcc52057b713:headline:ff7a3cf076ca7a3c",
      "before_evidence": "https://web.archive.org/web/20251203234418/https://www.junevity.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “Cell Reprogramming with siRNA” to “Reset gene networks to reverse disease, starting with siRNA for obesity”.",
      "between": {
        "from": "2025-12-03T23:44:18.000Z",
        "to": "2026-11-06T17:28:16.780Z"
      },
      "evidence": "https://www.junevity.com/",
      "evidence_kind": "live_capture",
      "basis": "page_facts",
      "topic": null
    }
  ],
  "update": {
    "headline": "Junevity updates homepage focus on siRNA and obesity",
    "summary": "Junevity’s homepage messaging has shifted over time from transcription factors and longevity toward cell reprogramming with siRNA and a stated focus on obesity. Recent wording emphasizes resetting gene networks to reverse disease, starting with siRNA for obesity.",
    "points": [
      {
        "text": "Between May 2024 and January 2025, Junevity changed its homepage headline from “TRANSCRIPTION FACTORS” to “CELL RESET FOR LONGEVITY”, which a classifier read as a repositioning.",
        "kind": "fact",
        "changes": [
          1
        ]
      },
      {
        "text": "This change between May 2024 and January 2025 suggests Junevity may have shifted emphasis toward longevity-focused cell reset.",
        "kind": "interpretation",
        "changes": [
          1
        ]
      },
      {
        "text": "Between January 2025 and December 2025, Junevity changed its homepage headline from “CELL RESET FOR LONGEVITY” to “Cell Reprogramming with siRNA”.",
        "kind": "fact",
        "changes": [
          2
        ]
      },
      {
        "text": "Between December 2025 and November 2026, Junevity changed its homepage headline from “Cell Reprogramming with siRNA” to “Reset gene networks to reverse disease, starting with siRNA for obesity”.",
        "kind": "fact",
        "changes": [
          3
        ]
      }
    ],
    "written_at": "2026-11-07T15:35:38.794Z",
    "basis": "ai_analysis",
    "model": "gpt-5.1-2025-11-13"
  },
  "method": {
    "version": "messaging-v1",
    "description": "https://startuphistory.org/method"
  },
  "license": "CC-BY-4.0",
  "cite": "StartupHistory, “Junevity” company record, https://startuphistory.org/c/junevity.com"
}