{
  "company": {
    "name": "Ionctura",
    "website": "https://ionctura.com/",
    "record": "https://startuphistory.org/c/ionctura.com"
  },
  "status": null,
  "history_since": "2018-06-20T21:41:06.000Z",
  "baseline": {
    "snapshot_id": "f3d774d04e585bdc5fc131a4b2a0cb7cc28c19ef0da7ff088f752f6a784e0a44",
    "observed_at": "2018-06-20T21:41:06.000Z",
    "headline": null,
    "description": "“Our goal is to modulate key culprits of immunosuppression in the tumour microenvironment to maximize the potential of checkpoint inhibitors.\" Catherine Pickering, CEO",
    "evidence": "https://web.archive.org/web/20180620214106/https://ionctura.com/",
    "evidence_kind": "internet_archive",
    "facts": null,
    "basis": "first_observation",
    "is_change": false
  },
  "live_captures": 1,
  "last_checked": "2026-11-06T17:26:21.192Z",
  "live_status": null,
  "messaging": [
    {
      "quote_observed_at": "2019-02-12T18:13:55.000Z",
      "variants": [
        {
          "headline": "iOnctura, modulate key culprits of immunosuppression tumour microenvironment",
          "subhead": "Our Pipeline We are developing a pipeline of carefully selected assets. Programs in oncology aim to harness both immune-mediated and direct anti-tumour activity to deliver superior clinical efficacy i",
          "observed_at": "2019-02-12T18:13:55.000Z",
          "evidence": "https://web.archive.org/web/20190212181355/https://www.ionctura.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "iOnctura, modulate key culprits of immunosuppression tumour microenvironment",
      "subhead": "Our Pipeline We are developing a pipeline of carefully selected assets. Programs in oncology aim to harness both immune-mediated and direct anti-tumour activity to deliver superior clinical efficacy i",
      "from": "2019-02-12T18:13:55.000Z",
      "to": "2019-02-12T18:13:55.000Z",
      "captures": 1,
      "evidence": "https://web.archive.org/web/20190212181355/https://www.ionctura.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "on": "2019-02-12T18:13:55.000Z"
      },
      "current": false
    },
    {
      "quote_observed_at": "2020-02-26T18:31:32.000Z",
      "variants": [
        {
          "headline": "Building on complementary mechanisms between cancer and fibrosis",
          "subhead": "Our Pipeline iOnctura’s pipeline contains an exquisitely selective PI3Kδ small molecule inhibitor which has just entered a phase I clinical trial in solid tumours, a second generation selective ATX sm",
          "observed_at": "2020-02-26T18:31:32.000Z",
          "evidence": "https://web.archive.org/web/20200226183132/https://www.ionctura.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "Building on complementary mechanisms between cancer and fibrosis",
      "subhead": "Our Pipeline iOnctura’s pipeline contains an exquisitely selective PI3Kδ small molecule inhibitor which has just entered a phase I clinical trial in solid tumours, a second generation selective ATX sm",
      "from": "2020-02-26T18:31:32.000Z",
      "to": "2020-02-26T18:31:32.000Z",
      "captures": 1,
      "evidence": "https://web.archive.org/web/20200226183132/https://www.ionctura.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "on": "2020-02-26T18:31:32.000Z"
      },
      "current": true
    }
  ],
  "changes": [
    {
      "n": 1,
      "id": "page-f3d774d04e585bdc5fc131a4b2a0cb7cc28c19ef0da7ff088f752f6a784e0a44:a46eb11c2cfe0458bb437e34b551d496b3b0c4c5cd37d30f38c23217d7f0c2ae:hiring:20dd4c09cc4ab0aa",
      "before_evidence": "https://web.archive.org/web/20180620214106/https://ionctura.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "hiring",
      "label": "Hiring",
      "summary": "Added a careers page.",
      "between": {
        "from": "2018-06-20T21:41:06.000Z",
        "to": "2019-02-12T18:13:55.000Z"
      },
      "evidence": "https://web.archive.org/web/20190212181355/https://www.ionctura.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/added-careers-page"
    },
    {
      "n": 2,
      "id": "page-a46eb11c2cfe0458bb437e34b551d496b3b0c4c5cd37d30f38c23217d7f0c2ae:249e6a7d7cc773d70cbebfc61d855121fed66bf5d7992963c158d205bcd70d21:headline:27ce5f74522a8d27",
      "before_evidence": "https://web.archive.org/web/20190212181355/https://www.ionctura.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “iOnctura, modulate key culprits of immunosuppression tumour microenvironment” to “Building on complementary mechanisms between cancer and fibrosis”.",
      "between": {
        "from": "2019-02-12T18:13:55.000Z",
        "to": "2020-02-26T18:31:32.000Z"
      },
      "evidence": "https://web.archive.org/web/20200226183132/https://www.ionctura.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
    },
    {
      "n": 3,
      "id": "page-3f171e12a39196f497a850e64473704dd03ef14e4117b4d0344a4a228e722bc9:be83e2822776c212684f80b9898e1d72a99884fff1690688bd38a4c478944f4b:funding:0efa4e2e20088c96",
      "before_evidence": "https://web.archive.org/web/20240812192231/https://www.ionctura.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "funding",
      "label": "Funding",
      "summary": "Announced on its homepage: “has played pivotal roles in scaling financial operations, raising over $400 million through private and public financings, and leading co…”.",
      "between": {
        "from": "2024-08-12T19:22:31.000Z",
        "to": "2025-07-10T13:53:54.000Z"
      },
      "evidence": "https://web.archive.org/web/20250710135354/https://www.ionctura.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/announced-funding"
    },
    {
      "n": 4,
      "id": "page-8e0b549028faabb966a8122682a12ed8230c1f6e8f35bf8b95b8db8caa6bd574:64767b93e7c4f7f02292ee01ae018de4b9a3bf461f536fcff8ddf87de6f79096:funding:0efa4e2e20088c96",
      "before_evidence": "https://web.archive.org/web/20261012003039/https://www.ionctura.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "funding",
      "label": "Funding",
      "summary": "Announced on its homepage: “has played pivotal roles in scaling financial operations, raising over $400 million through private and public financings, and leading co…”.",
      "between": {
        "from": "2026-10-12T00:30:39.000Z",
        "to": "2026-11-06T17:26:21.192Z"
      },
      "evidence": "https://www.ionctura.com/",
      "evidence_kind": "live_capture",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/announced-funding"
    }
  ],
  "update": null,
  "method": {
    "version": "messaging-v1",
    "description": "https://startuphistory.org/method"
  },
  "license": "CC-BY-4.0",
  "cite": "StartupHistory, “Ionctura” company record, https://startuphistory.org/c/ionctura.com"
}