{
  "company": {
    "name": "Arrakis Therapeutics",
    "website": "https://arrakistx.com/",
    "record": "https://startuphistory.org/c/arrakistx.com"
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        }
      ],
      "headline": "Discovering a new world of therapeutics - Arrakis TherapeuticsArrakis Therapeutics",
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      "to": "2019-01-16T03:38:24.000Z",
      "captures": 2,
      "evidence": "https://web.archive.org/web/20190116033824/http://arrakistx.com/",
      "evidence_kind": "internet_archive",
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          "to": "2019-01-16T03:38:24.000Z"
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    },
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        {
          "headline": "rSM progress. Destination patients. - Arrakis Therapeutics",
          "subhead": "The therapeutic potential of the human transcriptome, the set of all RNAs transcribed from DNA, remains largely unexplored. By harnessing new insights into RNA structure and dynamics, Arrakis is openi",
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          "evidence_kind": "internet_archive"
        },
        {
          "headline": "EXPEDITION RNA, DESTINATION PATIENTS",
          "subhead": "This is an example page. It’s different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduc",
          "observed_at": "2021-01-12T07:25:48.000Z",
          "evidence": "https://web.archive.org/web/20210112072548/https://arrakistx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "EXPEDITION RNA, DESTINATION PATIENTS",
          "subhead": "This is an example page. It’s different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduc",
          "observed_at": "2022-09-29T21:51:47.000Z",
          "evidence": "https://web.archive.org/web/20220929215147/https://arrakistx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "EXPEDITION RNA, DESTINATION PATIENTS",
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          "observed_at": "2023-07-01T18:29:54.000Z",
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        },
        {
          "headline": "EXPEDITION RNA, DESTINATION PATIENTS",
          "subhead": "This is an example page. It’s different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduc",
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      ],
      "headline": "EXPEDITION RNA, DESTINATION PATIENTS",
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      "to": "2024-07-08T14:50:27.000Z",
      "captures": 5,
      "evidence": "https://web.archive.org/web/20240708145027/https://arrakistx.com/",
      "evidence_kind": "internet_archive",
      "seen": {
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          "to": "2024-07-08T14:50:27.000Z"
        }
      },
      "current": false
    },
    {
      "quote_observed_at": "2026-11-05T11:27:53.143Z",
      "variants": [
        {
          "headline": "We turned ambition",
          "subhead": null,
          "observed_at": "2025-07-14T11:37:35.000Z",
          "evidence": "https://web.archive.org/web/20250714113735/https://arrakistx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "We turned ambition",
          "subhead": null,
          "observed_at": "2026-01-04T12:59:39.000Z",
          "evidence": "https://web.archive.org/web/20260104125939/https://arrakistx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "We turned ambition",
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          "observed_at": "2026-09-28T06:41:08.000Z",
          "evidence": "https://web.archive.org/web/20260928064108/https://arrakistx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "We turned ambition",
          "subhead": null,
          "observed_at": "2026-10-12T05:17:31.000Z",
          "evidence": "https://web.archive.org/web/20261012051731/https://arrakistx.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "We turned ambition",
          "subhead": null,
          "observed_at": "2026-11-05T11:27:53.143Z",
          "evidence": "https://arrakistx.com/",
          "evidence_kind": "live_capture"
        }
      ],
      "headline": "We turned ambition",
      "subhead": null,
      "from": "2025-07-14T11:37:35.000Z",
      "to": "2026-11-05T11:27:53.143Z",
      "captures": 5,
      "evidence": "https://arrakistx.com/",
      "evidence_kind": "live_capture",
      "seen": {
        "between": {
          "from": "2025-07-14T11:37:35.000Z",
          "to": "2026-11-05T11:27:53.143Z"
        }
      },
      "current": true
    }
  ],
  "changes": [
    {
      "n": 1,
      "id": "page-ec2e0f13366f759801950fa5f0cf40591016fe70fa3c84704742a0d6bda7f961:30b3b14cc6ac73f1b89924ed0c23f0f71f0c69e9751125dec628e616cdae24c8:headline:e87da9249fd81e90",
      "before_evidence": "https://web.archive.org/web/20190116033824/http://arrakistx.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “Discovering a new world of therapeutics - Arrakis TherapeuticsArrakis Therapeutics” to “rSM progress. Destination patients. - Arrakis Therapeutics”.",
      "between": {
        "from": "2019-01-16T03:38:24.000Z",
        "to": "2020-04-04T01:49:04.000Z"
      },
      "evidence": "https://web.archive.org/web/20200404014904/https://arrakistx.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
    },
    {
      "n": 2,
      "id": "page-fd4d86d0d804547368ec16ceee3e7a483c5de4a766571226e3e8262775ba0383:16cc3188a04e2653d7e5021ad43ba7fc1143c2bd213f8a41e8266113953919ff:headline:8ea3136cef1b51a9",
      "before_evidence": "https://web.archive.org/web/20240708145027/https://arrakistx.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “EXPEDITION RNA, DESTINATION PATIENTS” to “We turned ambition”.",
      "between": {
        "from": "2024-07-08T14:50:27.000Z",
        "to": "2025-07-14T11:37:35.000Z"
      },
      "evidence": "https://web.archive.org/web/20250714113735/https://arrakistx.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
    }
  ],
  "update": {
    "headline": "Arrakis Therapeutics updates homepage messaging",
    "summary": "Arrakis Therapeutics has changed its homepage headlines multiple times, reflecting shifts in how it presents its focus on therapeutics and patients.",
    "points": [
      {
        "text": "Between January 2019 and April 2020, Arrakis Therapeutics changed its homepage headline from “Discovering a new world of therapeutics - Arrakis TherapeuticsArrakis Therapeutics” to “rSM progress. Destination patients. - Arrakis Therapeutics”.",
        "kind": "fact",
        "changes": [
          1
        ]
      },
      {
        "text": "Between July 2024 and July 2025, Arrakis Therapeutics changed its homepage headline from “EXPEDITION RNA, DESTINATION PATIENTS” to “We turned ambition”.",
        "kind": "fact",
        "changes": [
          2
        ]
      },
      {
        "text": "These homepage headline changes between January 2019 and July 2025 may suggest evolving brand messaging around its therapeutic ambitions and orientation toward patients.",
        "kind": "interpretation",
        "changes": [
          1,
          2
        ]
      }
    ],
    "written_at": "2026-11-07T16:11:32.959Z",
    "basis": "ai_analysis",
    "model": "gpt-5.1-2025-11-13"
  },
  "method": {
    "version": "messaging-v1",
    "description": "https://startuphistory.org/method"
  },
  "license": "CC-BY-4.0",
  "cite": "StartupHistory, “Arrakis Therapeutics” company record, https://startuphistory.org/c/arrakistx.com"
}