{
  "company": {
    "name": "Arpeggio Biosciences",
    "website": "https://arpeggiobio.com/",
    "record": "https://startuphistory.org/c/arpeggiobio.com"
  },
  "status": null,
  "history_since": "2021-06-12T18:05:09.000Z",
  "baseline": {
    "snapshot_id": "5b08e5245b57ced0f98552309732386bd5520ac0617db18fffc7593328fbb0c5",
    "observed_at": "2021-06-12T18:05:09.000Z",
    "headline": "Map biology with functional genomics",
    "description": null,
    "evidence": "https://web.archive.org/web/20210612180509/https://www.arpeggiobio.com/",
    "evidence_kind": "internet_archive",
    "facts": null,
    "basis": "first_observation",
    "is_change": false
  },
  "live_captures": 0,
  "last_checked": null,
  "live_status": "offline",
  "messaging": [
    {
      "quote_observed_at": "2021-09-12T11:08:39.000Z",
      "variants": [
        {
          "headline": "Map biology with functional genomics",
          "subhead": null,
          "observed_at": "2021-06-12T18:05:09.000Z",
          "evidence": "https://web.archive.org/web/20210612180509/https://www.arpeggiobio.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Map biology with functional genomics",
          "subhead": null,
          "observed_at": "2021-09-12T11:08:39.000Z",
          "evidence": "https://web.archive.org/web/20210912110839/https://www.arpeggiobio.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "Map biology with functional genomics",
      "subhead": null,
      "from": "2021-06-12T18:05:09.000Z",
      "to": "2021-09-12T11:08:39.000Z",
      "captures": 2,
      "evidence": "https://web.archive.org/web/20210912110839/https://www.arpeggiobio.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "between": {
          "from": "2021-06-12T18:05:09.000Z",
          "to": "2021-09-12T11:08:39.000Z"
        }
      },
      "current": false
    },
    {
      "quote_observed_at": "2024-03-01T11:10:31.000Z",
      "variants": [
        {
          "headline": "Discovering drugs with systems biology",
          "subhead": null,
          "observed_at": "2022-09-07T13:24:48.000Z",
          "evidence": "https://web.archive.org/web/20220907132448/https://www.arpeggiobio.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Discovering drugs with systems biology",
          "subhead": null,
          "observed_at": "2023-01-11T17:17:44.000Z",
          "evidence": "https://web.archive.org/web/20230111171744/https://www.arpeggiobio.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Discovering drugs with systems biology",
          "subhead": null,
          "observed_at": "2023-09-26T12:16:01.000Z",
          "evidence": "https://web.archive.org/web/20230926121601/https://www.arpeggiobio.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Discovering drugs with systems biology",
          "subhead": null,
          "observed_at": "2024-03-01T11:10:31.000Z",
          "evidence": "https://web.archive.org/web/20240301111031/https://www.arpeggiobio.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "Discovering drugs with systems biology",
      "subhead": null,
      "from": "2022-09-07T13:24:48.000Z",
      "to": "2024-03-01T11:10:31.000Z",
      "captures": 4,
      "evidence": "https://web.archive.org/web/20240301111031/https://www.arpeggiobio.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "between": {
          "from": "2022-09-07T13:24:48.000Z",
          "to": "2024-03-01T11:10:31.000Z"
        }
      },
      "current": false
    },
    {
      "quote_observed_at": "2025-07-13T17:37:09.000Z",
      "variants": [
        {
          "headline": "Network biology meets drug discovery",
          "subhead": "We engineer medicine based not on a single target, but the biological network as a whole.",
          "observed_at": "2025-01-11T08:38:48.000Z",
          "evidence": "https://web.archive.org/web/20250111083848/https://www.arpeggiobio.com/",
          "evidence_kind": "internet_archive"
        },
        {
          "headline": "Network biology meets drug discovery",
          "subhead": "We engineer medicine based not on a single target, but the biological network as a whole.",
          "observed_at": "2025-07-13T17:37:09.000Z",
          "evidence": "https://web.archive.org/web/20250713173709/https://www.arpeggiobio.com/",
          "evidence_kind": "internet_archive"
        }
      ],
      "headline": "Network biology meets drug discovery",
      "subhead": "We engineer medicine based not on a single target, but the biological network as a whole.",
      "from": "2025-01-11T08:38:48.000Z",
      "to": "2025-07-13T17:37:09.000Z",
      "captures": 2,
      "evidence": "https://web.archive.org/web/20250713173709/https://www.arpeggiobio.com/",
      "evidence_kind": "internet_archive",
      "seen": {
        "between": {
          "from": "2025-01-11T08:38:48.000Z",
          "to": "2025-07-13T17:37:09.000Z"
        }
      },
      "current": true
    }
  ],
  "changes": [
    {
      "n": 1,
      "id": "classifier-7a16c48275bdd62a995ace5a1ce793c3d1c7a11af83daadacfc9484613c477ac:219e9d97e0b601f41f065d9b0a2a4f78f2b5041ded4c18a0674aee5bc73eba7e:repositioning",
      "before_evidence": "https://web.archive.org/web/20210912110839/https://www.arpeggiobio.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "repositioning",
      "label": "Messaging",
      "summary": "Changed its homepage headline from “Map biology with functional genomics” to “Discovering drugs with systems biology”.",
      "between": {
        "from": "2021-09-12T11:08:39.000Z",
        "to": "2022-09-07T13:24:48.000Z"
      },
      "evidence": "https://web.archive.org/web/20220907132448/https://www.arpeggiobio.com/",
      "evidence_kind": "internet_archive",
      "basis": "classifier",
      "topic": "https://startuphistory.org/t/repositioned"
    },
    {
      "n": 2,
      "id": "page-219e9d97e0b601f41f065d9b0a2a4f78f2b5041ded4c18a0674aee5bc73eba7e:c60a761cf01d8af6fea0a3c9f3c39a296da35aa2717b9887dbb55ef61886c842:funding:694ac26f103403e6",
      "before_evidence": "https://web.archive.org/web/20220907132448/https://www.arpeggiobio.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "funding",
      "label": "Funding",
      "summary": "Announced on its homepage: “arpeggio Arpeggio Bio Raises Series A Discovering drugs with systems biology We apply high-throughput transcriptomics to match drugs to a…”.",
      "between": {
        "from": "2022-09-07T13:24:48.000Z",
        "to": "2023-01-11T17:17:44.000Z"
      },
      "evidence": "https://web.archive.org/web/20230111171744/https://www.arpeggiobio.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/announced-funding"
    },
    {
      "n": 3,
      "id": "page-8b055c087fb1c7fba0aedd88f3cb2806902dd7e17490cc8ae2943d0abe9a7be3:053755b7bd8e7cb24aabab620d8391968a0ad14b487cc8803c17b149abf4d675:funding:015f89be86326694",
      "before_evidence": "https://web.archive.org/web/20240301111031/https://www.arpeggiobio.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "funding",
      "label": "Funding",
      "summary": "Announced on its homepage: “Arpeggio Raises $17M in Series A We have partnered with Builders VC, and many returning investors, to develop our pipeline of transcripto…”.",
      "between": {
        "from": "2024-03-01T11:10:31.000Z",
        "to": "2025-01-11T08:38:48.000Z"
      },
      "evidence": "https://web.archive.org/web/20250111083848/https://www.arpeggiobio.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/announced-funding"
    },
    {
      "n": 4,
      "id": "page-8b055c087fb1c7fba0aedd88f3cb2806902dd7e17490cc8ae2943d0abe9a7be3:053755b7bd8e7cb24aabab620d8391968a0ad14b487cc8803c17b149abf4d675:headline:2122ca12f570d35a",
      "before_evidence": "https://web.archive.org/web/20240301111031/https://www.arpeggiobio.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "headline",
      "label": "Headline",
      "summary": "Changed its homepage headline from “Discovering drugs with systems biology” to “Network biology meets drug discovery”.",
      "between": {
        "from": "2024-03-01T11:10:31.000Z",
        "to": "2025-01-11T08:38:48.000Z"
      },
      "evidence": "https://web.archive.org/web/20250111083848/https://www.arpeggiobio.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": null
    },
    {
      "n": 5,
      "id": "page-053755b7bd8e7cb24aabab620d8391968a0ad14b487cc8803c17b149abf4d675:74e832db9dadd703f3e8f201d4cc5075fa93c8247fe5d414a8b20515efabdec7:funding:015f89be86326694",
      "before_evidence": "https://web.archive.org/web/20250111083848/https://www.arpeggiobio.com/",
      "before_evidence_kind": "internet_archive",
      "kind": "funding",
      "label": "Funding",
      "summary": "Announced on its homepage: “Arpeggio Raises $17M in Series A We have partnered with Builders VC, and many returning investors, to develop our pipeline of transcripto…”.",
      "between": {
        "from": "2025-01-11T08:38:48.000Z",
        "to": "2025-07-13T17:37:09.000Z"
      },
      "evidence": "https://web.archive.org/web/20250713173709/https://www.arpeggiobio.com/",
      "evidence_kind": "internet_archive",
      "basis": "page_facts",
      "topic": "https://startuphistory.org/t/announced-funding"
    }
  ],
  "update": {
    "headline": "Arpeggio Biosciences highlights Series A and updated drug discovery framing",
    "summary": "Arpeggio Biosciences has updated its homepage messaging around drug discovery and disclosed a Series A raise. Recent homepage text emphasizes “network biology” and a $17M Series A involving Builders VC and returning investors.",
    "points": [
      {
        "text": "Between September 2021 and September 2022, Arpeggio Biosciences changed its homepage headline from “Map biology with functional genomics” to “Discovering drugs with systems biology”.",
        "kind": "fact",
        "changes": [
          1
        ]
      },
      {
        "text": "Between September 2022 and January 2023, the homepage announced “arpeggio Arpeggio Bio Raises Series A Discovering drugs with systems biology We apply high-throughput transcriptomics to match drugs to a…”.",
        "kind": "fact",
        "changes": [
          2
        ]
      },
      {
        "text": "Between March 2024 and January 2025, Arpeggio Biosciences’ homepage stated “Arpeggio Raises $17M in Series A We have partnered with Builders VC, and many returning investors, to develop our pipeline of transcripto…”.",
        "kind": "fact",
        "changes": [
          3
        ]
      },
      {
        "text": "Between March 2024 and January 2025, the homepage headline changed from “Discovering drugs with systems biology” to “Network biology meets drug discovery”, which suggests an emphasis on network biology language in describing its work.",
        "kind": "interpretation",
        "changes": [
          4
        ]
      }
    ],
    "written_at": "2026-11-07T15:41:16.626Z",
    "basis": "ai_analysis",
    "model": "gpt-5.1-2025-11-13"
  },
  "method": {
    "version": "messaging-v1",
    "description": "https://startuphistory.org/method"
  },
  "license": "CC-BY-4.0",
  "cite": "StartupHistory, “Arpeggio Biosciences” company record, https://startuphistory.org/c/arpeggiobio.com"
}